Comps, honors papers, and prize-winning works of the Biology Department are featured here. All works have been self-submitted by the student authors. Descriptive information about each work is available to search or browse. Access to the full text of the works is limited to current Carleton affiliates with faculty permission. Learn more about how to submit your work and how to request access to the full text of works.

In addition to this digital archive, physical copies of past Biology comps are available for browsing in the Biology office (Hulings Hall 214).

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Submissions from 2017

Andrew Benjamin Bernstein, Biology (BIOL) 2017, Antioxidants are not the Cure: Glutathione-mediated Redox Homeostasis Promotes Cancer Initiation and Survival

Kharmen Bharucha, Biology (BIOL) 2017, Dendritic Cells: Crucial Mediators of Chemotherapy Response and Resistance

Alexandra Lee Braiedy, Biology (BIOL) 2017, Abiotic drivers of regime shifts in shallow benthic polar communities

Claire Anne Branigin, Biology (BIOL) 2017, The Consequences of Broad-Spectrum Antibiotic Use for the Invasibility of the Gut Microbiome

Samuel Hunter Brown, Biology (BIOL) 2017, Environmental Stress and a Model for Epigenetic Inheritance

Felicity Renate Baxter Carroll, Biology (BIOL) 2017, Is Specialization a Dead End? Effects of Specialization on Evolutionary Success

Cynthia Chang, Biology (BIOL) 2017, Role of p300/CBP Histoneacetyltransferase Activity in Long Term Memory Formation of the Hippocampus

Lisa Cheung, Biology (BIOL) 2017, Activation of SREBPs induce de novo lipogenesis to support tumorigenesis in cancer cells

Rachel Stephanie Cheung, Biology (BIOL) 2017, Expansion of the Outer Subventricular Zone in the Neocortex: aRG Differentiation & bRG Proliferation

Allison Lee Clark, Biology (BIOL) 2017, Understanding the mechanism of Myc-induced glutamine addiction in cancer cells

Laina Cross, Biology (BIOL) 2017, Evolutionarily Conserved Regulatory Programs Inform Treatments for Myocardial Infarction

Cyrus James Deloye, Biology (BIOL) 2017, Evolution within the urban environment: the two mechanisms of human driven genetic variation

Jinhong Dong, Biology (BIOL) 2017, Macrophage Activation and Extracellular Matrix Destruction in Tuberculosis

Kelly Elizabeth Fahrner-Scott, Biology (BIOL) 2017, Tumor-associated macrophages and vascular endothelial growth factor in the tumor microenvironment

Emily Huang, Biology (BIOL) 2017, Stress-Induced DNA Methylation and MicroRNA Regulation Lead to Stress Vulnerability and Resilience

Joyce Kim, Biology (BIOL) 2017, The STING pathway: molecular mechanisms and potential for innovative cancer immunotherapy

Saehee Lee, Biology (BIOL) 2017, Autism spectrum disorder (ASD): a model for epigenetic modifications

Lalangi Shanika Marasinghe, Biology (BIOL) 2017, What in hydroxylation! Hypoxic tumor environments reduce the ability of lysyl hydroxylase 2 to induce collagen deposition

Patton Craig McClelland, Biology (BIOL) 2017, R-Smads mediate the dual nature of TGF-β1 signaling in inflammatory bowel disease

Kazia Mermel, Biology (BIOL) 2017, Sex gets hotter: Evolutionary responses of reptile sex determination to climate change

Jeanne G. Moua, Biology (BIOL) 2017, M2 Macrophage Polarization and Tumor Invasion: Regulating Anti-Inflammatory NF-kB

Kyle Martin Mou, Biology (BIOL) 2017, Autophagy-mediated aerobic glycolysis in the tumor stroma supports oxidative metabolism in cancer cells: metabolic coupling in the tumor microenvironment

Justin Ross Nathan, Biology (BIOL) 2017, Cardiac Fibroblasts as the Primary Drivers of Cardiac Fibrosis: A Study of Injury-Induced miRNA Dysregulation

Aidan Thomas Murphy Neher, Biology (BIOL) 2017, DNA methylation transformations essential to cocaine action

Amelia Julie Neilson, Biology (BIOL) 2017, The Flux Capacity: A mechanism for PCK-driven glutamine utilization and mTORC1 activation in cancer

Lauren Tolkemitt Pflughoeft, Biology (BIOL) 2017, Salmon migratory adaptation in the Anthropocene

Koehler Ray Powell, Biology (BIOL) 2017, Born This Way: Transgenerational Epigenetic Transmission of Preconception Stress

Maud Hudson Prineas, Biology (BIOL) 2017, Immune Checkpoint Inhibitors: Tumor Destruction Using Immunotherapy

Jackson Friedrich Raynor, Biology (BIOL) 2017, Crosstalk between signaling pathways: A holistic approach to understanding fibrosis

Georgia M. Schmitt, Biology (BIOL) 2017, Causes and cures for psychiatric illness: An examination of microRNA’s role in regulating behavior

Kaylee Shiao, Biology (BIOL) 2017, The Role of HOX Genes in Patterning and Development in the Fin-To-Limb Transition

Ryann Elizabeth Shor, Biology (BIOL) 2017, There Will Be Blood: Vascular Mimicry Perpetuates an Aggressive Cancer Phenotype

Katherine Prothero Sperry, Biology (BIOL) 2017, Ocean warming and receding sea ice drive the changing biogeography of kelps

Brett Eric Sterk, Biology (BIOL) 2017, Dynamic DNA Methylation as an Essential Epigenetic Regulator of Memory Consolidation

Geraldine Tellbuescher, Biology (BIOL) 2017, The Role of DNA Methylation and Histone Methylation in Addictive Behavior

Ka Thao, Biology (BIOL) 2017, Photodynamic Therapy Induces Immunogenic Cell Death in Cancer Cells

Maria Wetzel, Biology (BIOL) 2017, A BCL-2 Family Affair: Apoptotic proteins, metabolism, and chemosensitivity

Rebecca Wiersma, Biology (BIOL) 2017, The role of dynamic DNA methylation in long-term memory consolidation

Submissions from 2016

Besim Ademi, Biology (BIOL) 2016, The Role of the Gut Microbiota in Inflammatory Bowel Disease

Dani Mae Andrusko, Biology (BIOL) 2016, Coming of Age: Morphological maturation of Pseudomonas aeruginosa biofilm is dependent on extracellular DNA

Anais Elena Boyd, Biology (BIOL) 2016, Decoupling C and N cycles: Drought differentially affects plant and microbial activity in arid ecosystems

Amelia Marie Campbell, Biology (BIOL) 2016, Mechanisms of Centrally-Mediated Skeletal Muscle Fatigue: Small Fibers Have a Big Impact

Senya Rae Combs, Biology (BIOL) 2016, A mesoscopic model for force generation in Listeria monocytogenes

Kathryn Rae Crofton, Biology (BIOL) 2016, Mom Teaches Tolerance: Breast Milk, Gut Microbes, and the Induction of Foxp3+ Regulatory T Cells

Jlor Mesa Dizon, Biology (BIOL) 2016, The directionality of neural crest migration relies on chemotactic signaling to counterbalance contact inhibition of locomotion

Patrick H. England, Biology (BIOL) 2016, Codon Usage Bias: A Not So Silent Mechanism in Regulating Gene Expression

Thomas Rickey Felton, Biology (BIOL) 2016, Junction-Mediated and Regulatory Protein Connects Cellular Adhesion and Protrusion Regulatory Pathways.

Jeremy Adams Fisher, Biology (BIOL) 2016, A Specialist in a Strange Land: The Role of Multi-Species Interactions and Non-Adaptive Mechanisms in Lepidoptera Specialization

Samuel Evan Greaves, Biology (BIOL) 2016, The Silent Treatment: The Consequences of Synonymous Codon Selection In Exonic Binding Sites

Sara Elizabeth Hastings, Biology (BIOL) 2016, Storm runoff pulses and their effects on phytoplankton community composition and primary productivity in estuaries

Jody He, Biology (BIOL) 2016, Need for Speed: The Role of Translational Efficiency in Codon Usage Bias

Ellis Sweet Johnston, Biology (BIOL) 2016, Sequestration of Plant Metabolites and its Varied Usage by Generalist and Specialist Herbivores

Prasidda Khadka, Biology (BIOL) 2016, Reprogramming of the immune cells by gut microbiota plays an important role in anti-tumor immunity

Megan Marie King, Biology (BIOL) 2016, Microbial Metabolites as Messengers: Bifidobacterium uses metabolites to modulate dendritic cell maturation, differentiation, and function with implications to Celiac Disease

Julia Krumholz, Biology (BIOL) 2016, Lyme Disease Host Frequencies Change in Response to Acorn Masts, Altering Prevalence of Borrelia Burgodorferi in Northeast American Environments

Alexander Richard Kulacki, Biology (BIOL) 2016, Generalists and Specialists in Response to Ecological Disturbance

Abhimanyu Lele, Biology (BIOL) 2016, Causes of Individual Foraging Specialization

de Macedi Khuaten Maaneb, Biology (BIOL) 2016, The role of carbohydrate subtypes in T cell population modification, intestinal epithelial cell tight junction integrity, and autoimmune disease

Matthew Allen Mensinger, Biology (BIOL) 2016, The Ecological Influences of Semelparous Salmon and Anthropogenic Nutrient Subsidies in Riparian Systems

Darcy Mishkind, Biology (BIOL) 2016, A Codon of Silence: The effects of synonymous codon optimization and de-optimization on translation

Anya Moradian, Biology (BIOL) 2016, Commissural axons require additional cues that modulate the Netrin pathway and ensure proper guidance

Christopher William Nootenboom, Biology (BIOL) 2016, Whale Falls and the Species-Energy Theory: Dual Resource Pulses that Promote Global Diversity as Evolutionary Stepping Stones

Jordan Marie Pruszenski, Biology (BIOL) 2016, Examining migratory ungulates as a resource pulse and their effects on the species in their migratory range

Shraddha Raghavan, Biology (BIOL) 2016, Extracellular matrix components play a critical role in the segmental migration of trunk neural crest cells

Andy Rodgers, Biology (BIOL) 2016, Understanding host shifts in phytophagous insects and their role in diversification

Brittany Salazar, Biology (BIOL) 2016, Effect of gut microbiome on TH17 cell activation and Toll-like receptor signaling in rheumatoid arthritis development

Roberto Stephen Sande, Biology (BIOL) 2016, The Netrin-1/DCC/ERK Pathway and its Effects on Axonal Branching

Grace Marie Sassana, Biology (BIOL) 2016, Feeding Our Immune Systems: Microbiota-Derived Short Chain Fatty Acids Regulate Colonic Foxp3+ Regulatory T Cell Generation

Cameron Meyer Shorb, Biology (BIOL) 2016, Factors regulating invasive plant responses to resource pulses

Bing Shui, Biology (BIOL) 2016, Gastric Cancer Metastasis: Epithelial-Mesenchymal Transition Promoted By Cancer-Associated Fibroblasts

Ximou Song, Biology (BIOL) 2016, Synonymous Codon Bias in Translational Elongation and Protein Folding

Christopher Ely Sundquist, Biology (BIOL) 2016, Commensal Communication: An Examination of the Bacteroides fragilis Polysaccharide A Dependent Immunosuppressive Pathway

Gail J. Waltz, Biology (BIOL) 2016, Synonymous Codon Use: Effects on Ribosome Speed, Protein Folding, and Protein Function

Ryan David Wegner, Biology (BIOL) 2016, Periodic Cicadas as a Resource Pulse

Samuel West, Biology (BIOL) 2016, The roll of the cytokine CXCL12 and its receptor CXCR4 in the metastasis of tumor cells in breast cancer

Samuel William White, Biology (BIOL) 2016, Maintenance of DUOX-pathway Homeostasis in the Drosophila Gut

Richard Michael Yeker, Biology (BIOL) 2016, ROS/RNS impair sarcoplasmic reticulum calcium release and decrease calcium sensitivity to induce skeletal muscle fatigue

Submissions from 2015

Shamis M. Adam, Biology (BIOL) 2015, Antiviral Immunity: Interactions between Inhibitory Killer-Cell Immunoglobulin-like Receptors and MHC-I Molecules in HIV Infection

Jae Ahn, Biology (BIOL) 2015, Canonical and Non-Canonical Wnt Signaling Pathways Regulate Dendritic Morphogenesis and Synaptogenesis in Hippocampal Neurons

Laura Christine Arneson, Biology (BIOL) 2015, From Burger to Tumor: The Role of Diet-Derived Glycans in Cancer

Hillary Kraemer Barbetta, Biology (BIOL) 2015, Exploring and enhancing the regenerative potential of the mammalian heart through exogenous cardiomyocyte differentiation and transplantation

Emily Virginia Buckner, Biology (BIOL) 2015, Making Connections in Human-dominated Landscapes: The Ecological Role of Subsidies in Recipient Systems

Colette Celichowski, Biology (BIOL) 2015, The Great Xscape: How and Why Genes Escape Inactivation on the Eutherian Xi

Ruisu Chen, Biology (BIOL) 2015, N-ε-carboxymethyl-lysine (CML) binds to the receptor for AGE (RAGE) and activates multiple pathways that lead to the development of atherosclerosis complications in diabetes patients

Louis David Cohen, Biology (BIOL) 2015, Dosage Compensation Models in C. elegans compared to those in D. melanogaster

Laura Legendre Colbran, Biology (BIOL) 2015, An Exiting Existence: mechanisms of mammalian sex chromosome inactivation

Wenyue College, Biology (BIOL) 2015, Multiple pathways are required for hypoxia-induced autophagy - a survival mechanism of cancer cells

Alison Carol Coogan, Biology (BIOL) 2015, Nephron segmentation and its application in advancing regenerative therapies for kidney disease

Daniel David Cook, Biology (BIOL) 2015, Regulation of the Ferric Uptake Regulator through Extracellular Cell Wall Iron Storage Drives an Accumulation of Intracellular Iron during the Lag Phase of Staphylococcus aureus

Hannah Marit Curtiss, Biology (BIOL) 2015, Aberrant O-Mannose Initiated Glycosylation of ?-Dystroglycan Underlies Congenital Muscular Dystrophies

Leigh Dairaghi, Biology (BIOL) 2015, Mechanisms of mammalian dosage compensation: X-chromosome inactivation and reactivation

John Alexander Ficklin, Biology (BIOL) 2015, Predation in the City

Lily Rose Gage, Biology (BIOL) 2015, Effects of human-mediated habitat change on parasite prevalence and transmission

Alexandra Nicole Guy, Biology (BIOL) 2015, Mechanisms behind the disintegration of the midline epithelial seam in palatogenesis and implications for cleft palate

Alison Elizabeth Hall, Biology (BIOL) 2015, Ecosystem and Community Consequences of Size Selective Fishing

Anthony Lamar Harris, Biology (BIOL) 2015, An Increase from the Normal Homeostatic Temperature of Photorhabdus asymbiotica Induces Weakened Virulence Capabilities

Emily Jo Hillmer, Biology (BIOL) 2015, The Role of Aberrantly Glycosylated MUC1 in Mechanisms of Breast Cancer Metastasis

Kyle John Kasten, Biology (BIOL) 2015, Variation in corridor habitat requirements between predator and prey species

Shiou-Yuh Lin, Biology (BIOL) 2015, Dosage Compensation through X Chromosome Inactivation

Jacky Lu, Biology (BIOL) 2015, Got Guts to be a Killer? The Role of Natural Killer Cells in Gut Mucosal Immunity