Comps, honors papers, and prize-winning works of the Biology Department are featured here. All works have been self-submitted by the student authors. Descriptive information about each work is available to search or browse. Access to the full text of the works is limited to current Carleton affiliates with faculty permission. Learn more about how to submit your work and how to request access to the full text of works.

In addition to this digital archive, physical copies of past Biology comps are available for browsing in the Biology office (Hulings Hall 214).

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Submissions from 2020

Cecily Choy, Biology (BIOL) 2020, The Role of Autoimmunity in Primary Ovarian Insufficiency: A Proposed Mechanism of Attack

Darryl Colcol, Biology (BIOL) 2020, KV1.3: An Ionic Driving Force for Neural Degradation

Thais Del Rosario Hernandez, Biology (BIOL) 2020, The Role of Asymmetry in Epithalamic Structures on Psychiatric Disorders

Hannah Eglinton, Biology (BIOL) 2020, Regulating Antigen Stimulation to Improve Memory Formation and Mitigate Exhaustion in CAR T Cells

Jithran Ekanayake, Biology (BIOL) 2020, Preliminary Model for a Biomimetic Space Radiation Shield

Estee Emlen, Biology (BIOL) 2020, Helminth Parasites and Allergens Initiate Type 2 Immune Responses by Inducing IL-25 and IL-33 Signaling to Type 2 Innate Lymphoid Cells

Maria Fairchild, Biology (BIOL) 2020, Redox or Detox? The Role of the Ladderane Lipid Membrane in Anammox Metabolism

Emma Ferrer, Biology (BIOL) 2020, Mechanisms for Modulating Cytokine Release Syndrome (CRS) after Chimeric Antigen Receptor (CAR) T-cell Therapy

David Galambos, Biology (BIOL) 2020, RNA Transcripts Assemble Nuclear Bodies That Regulate Chromatin Organization and Transcription Machinery

Seth Greengo, Biology (BIOL) 2020, N-6-Methyladenosine Promotes HIV Replication through Its Interactions with Host YTHDF Proteins

Josh Hauser, Biology (BIOL) 2020, Wingbeat Frequency Negatively Correlates with Flexural Stiffness to Mitigate Damage in Birds with Rapid Wingbeats

Adam Hruby, Biology (BIOL) 2020, Is This Canon? Both Replicative and Oncogene-Induced Cellular Senescence Activate the Canonical NF-κB Pathway, but Only Oncogene-Induced Senescence Activates the Noncanonical NF-κB Pathway

Christopher Jabbarpour, Biology (BIOL) 2020, Destabilization of Fish Schooling Behavior Due to a Changing Climate

Abby Jackson, Biology (BIOL) 2020, Allogeneic DAP12-based CAR NK Cells as an Anti-HIV Immunotherapy to Target the Latent Viral Reservoir

Daniel Johnson, Biology (BIOL) 2020, Engineering Safety Switches to Manage the Toxicities of CAR T Cell Therapy

Kamran Kelly, Biology (BIOL) 2020, Driving Out Autoimmunity: Generating a CAR T Regulatory Cell Against Multiple Sclerosis

Hannah Kennicott, Biology (BIOL) 2020, Confirming Diurnal Oscillations and Scrutinizing the Potential Circadian Rhythm of the Gut Microbiome

Caroline Kern-Allely, Biology (BIOL) 2020, Inclusion of the Landscape of Fear and Mesopredator Release in a Trophic Cascade Model to Predict Effects of Apex Predator Extirpation

Rebekah Kissel, Biology (BIOL) 2020, Polycystic Ovarian Syndrome: GABA Mediated Neuroendocrine Origins

Oleksandr Kyrysyuk, Biology (BIOL) 2020, Boolean Logic-Gated CAR T Cells with TCR Mimic Recognition Overcome Critical Antigen Targeting Barrier in Solid Tumors

Emma Lederer, Biology (BIOL) 2020, CD28 CAR Regulatory T cells Prevent Graft Rejection and Graft-Versus-Host Disease

Joe Lewis, Biology (BIOL) 2020, Pleistocene Megafauna Extinction: Combining Prehistoric Data with Modern Experiments to Determine the Impact on Vegetation

Brendon Lin, Biology (BIOL) 2020, Oxygen and Temperature May Be Able to Predict Size-based Responses to Global Warming in Polar Waters

Quinn McVeigh, Biology (BIOL) 2020, The Complex Interplay of MicroRNAs and N6-methyladenosine Modifications for Precise Control of Messenger RNA Levels

Tanvi Mehta, Biology (BIOL) 2020, A Twisted Gut: Understanding Left-Right Asymmetry in Gut Morphogenesis

Cameron Meikle, Biology (BIOL) 2020, Alternative Roles for m6A Modifications During Flaviviridae Infection

Fletcher Metz, Biology (BIOL) 2020, A Bispecific CD8+ CAR-T Cell Therapy Optimized for Persistence, Exhaustion Resistance, Immunity from HIV, and Prevention of HIV Immune Escape

Ada Meyer, Biology (BIOL) 2020, Impacts of Microplastics on Particle Flux and the Biological Pump in a Warming Ocean

Keenan Moore, Biology (BIOL) 2020, Plastic Pollutants: Bisphenol A and Its Effects on Male Fertility

Sarah Newsham, Biology (BIOL) 2020, Predicted Increase in Phytoplankton Abundance due to Climate Change: Importance of Top-Down and Bottom-Up Controls

Fin Ouweleen, Biology (BIOL) 2020, The Plumage Problem: Presence of Bird Display Is Affected by Selective Pressures from Parasitization and Predation

Annalise Peebles, Biology (BIOL) 2020, From Surface Water to Sediment: How Warming Temperatures Influence the Deposition of Microplastics in Marine and Freshwater Systems

Conrad Phelan, Biology (BIOL) 2020, The Cytoskeleton Is the Decisive Factor in C-Looping in the Chick Heart

Maya Powell, Biology (BIOL) 2020, Branching Corals Are Disproportionately Susceptible to Ocean Acidification Based on Diffusive Boundary Layer Variation

Peter Richieri, Biology (BIOL) 2020, Molecular to Organismal Chirality; a Possible Blueprint for Establishing Left-Right Asymmetry in the Bilateria

Katherine Rigney, Biology (BIOL) 2020, The Effects of Vessel Noise on Bottlenose Dolphins (Tursiops sp.): Energetic Costs and Budgeting

Brian Rivera, Biology (BIOL) 2020, Indole Be All: E. coli Indole Production in Response to Stress

Mikkel Sawyer, Biology (BIOL) 2020, Structural RNA Against the World (of Antibiotic Microbial Resistance): Riboswitches and Ribo- Regulators as Targets for Novel Antibiotic Therapies

Kaylin Steinberg, Biology (BIOL) 2020, Harnessing PD-1 in the Construction of HIV-Specific CAR-T Cells to Induce a Localized “Shock and Kill” of the Latent Viral Reservoir

Nina Strand, Biology (BIOL) 2020, Invasive Marine Predators - Why Are There Not More of Them?

Anika Thomas, Biology (BIOL) 2020, Asymmetrical Mammary Gland Development: A Genetic Predisposition to Left-Sided Breast Cancer

Tam Tieu, Biology (BIOL) 2020, Understanding Stem Memory T Cell Development and Differentiation to Combat HIV

Kevin Tran, Biology (BIOL) 2020, The Orphan Methyltransferase CcrM Is an Epigenetic Regulator for Multiple Bacteria

Hannah Uttley, Biology (BIOL) 2020, The Role of Microglial Ion Channel P2X7 in Depression

Margriet VanDerwerker, Biology (BIOL) 2020, The Role of HLA-A2 CAR T Regulatory Cell Therapy, Foxp3, and CTLA-4 in Hematopoietic Stem Cell Transplantation

Alex Whitis, Biology (BIOL) 2020, Marine Sessile Animals: Adaptations For Feeding And Implications Of Climate Change

Evan Wright, Biology (BIOL) 2020, The Therapeutic Potential of Kv1.3 Inhibition by PAP-1 for the Treatment of Alzheimer’s Disease

Submissions from 2019

Proud Chanarat, Biology (BIOL) 2019, Tracing Back to the Gene Content of the Last Universal Common Ancestor: Approaches in Taking Horizontal Gene Transfer into Account

Kristina Conrad, Biology (BIOL) 2019, The behavior of nectar robbers and effects on flowering plants for mutualism maintenance

Amanda Crawford, Biology (BIOL) 2019, Epigenetic Regulation of APOE in the Etiology and Progression of Late Onset Alzheimer’s Disease

Jackie Culotta, Biology (BIOL) 2019, How is honesty maintained in colorful condition dependent mate quality advertisements? The roles of costly signals and indicator traits

Mallika Dargan, Biology (BIOL) 2019, Langerhan cells, Langerin, and HIV transmission in the Female Reproductive Tract

Tris Dodge, Biology (BIOL) 2019, The curious case of the cane toad (Rhinella marina): using local context to predict top-down trophic cascades driven by invasive, allelochemically-defended prey

Fayzeh El Banna, Biology (BIOL) 2019, Epigenetics of BDNF Gene in PTSD Intense Fear Memory Formation and Lack of Extinction

Logan Emholtz, Biology (BIOL) 2019, Enhancing Skeletal Muscle Mitochondrial Biogenesis: The Effects of Endurance Training and Glycogen Levels

Roger Faust, Biology (BIOL) 2019, Invasive Ecosystem Engineers in a Non-Native Habitat: Ecological Impacts of Zebra Mussel Induced Nutrient Shifts

Lauren Goboff, Biology (BIOL) 2019, Gene Expression Disruption as a Model for Tissue Specificity in Laminopathies

Clara Hobbie, Biology (BIOL) 2019, Zika Virus Infection of Placental Macrophages Leads to Placental Dysfunction and Subsequent Fetal Demise

Anna Huber, Biology (BIOL) 2019, Relating Nutrition to Alzheimer's Disease Pathology Through Sirt1-Dependent H4K16 Deacetylation

Adriana Hudson, Biology (BIOL) 2019, Induction of Senescence by Progerin in Hutchinson Gilford Progeria Syndrome (HGPS) Cells is Not Reliant on Oxidative Stress

Lon Hutchinson, Biology (BIOL) 2019, Epigenetic Modulation in Multiple Sclerosis Therapeutics: The Potential of SIRT1

Phuoc Thuan Huynh, Biology (BIOL) 2019, Inhibition of Enhancer of Zeste Homolog 2 Reduces Tumor-Initiating Ability of Cancer Stem Cells and Induces Proinflammatory T Cell Responses in Glioblastoma Multiforme

Callen M. Inman, Biology (BIOL) 2019, Why are some mimics more precise than others?: how predator psychology drives the evolution of imperfect Batesian mimicry

Anna Karmel, Biology (BIOL) 2019, The Evolution of Sexually Deceptive Pollination in Orchidaceae

Pavana Khan, Biology (BIOL) 2019, Lamin A/C Uses Two Pathways to Synergistically Regulate Mechanosensitive Differentiation

Dimitri Laing, Biology (BIOL) 2019, Stress, Trauma, and ACEs Define Epigenetic Fate

Annabelle Leahy, Biology (BIOL) 2019, Lung Resident CD8+ T cells: Crucial Players in Rapid Clearance of Influenza Infection

Cecilia Ann Leone, Biology (BIOL) 2019, Chronology of Selective Responses against X-Chromosome Meiotic Drive Determined by Existing Climate and Population Genetics: Temperature and the Evolution of Mating Behavior, Suppressors, and Female Choice

Kaitlin Libbey, Biology (BIOL) 2019, The direct and indirect effects of warming on methane emissions from peatlands

Henry Liedl, Biology (BIOL) 2019, A Review of Histone Dynamics in the Nucleus Accumbens as a Result of Cocaine Exposure

Viola Li, Biology (BIOL) 2019, New Model for the Origin of Animal Multicellularity: From Temporal to Spatial Cell Differentiation, Advancements in GRNs

Will Loner, Biology (BIOL) 2019, Insect Outbreaks as a Potent Control Over Carbon and Nitrogen Flux: Effects, Feedbacks and Complications of Climate Change

Becky Luh, Biology (BIOL) 2019, HIV Initiation of a Microbial Translocation and Inflammation Cycle

Hailey Mair, Biology (BIOL) 2019, Interplay of DNMT3B and TET enzymes in reducing differentially methylated regions of iPSCs and hESCs

Jessica Makori, Biology (BIOL) 2019, Phenotypic Plasticity as a Metabolic Strategy for Plasmodium falciparum in Malaria Transmission

Aislinn N. Mayfield, Biology (BIOL) 2019, On Protocell formation: The co-assembly of a lipid compartment, informational polymer and catalytic network

Alief Moulana, Biology (BIOL) 2019, The pangenome paradox of the environmental microbes: between the adaptive accessory genome and the within-species genomic diversity

David O'Dea, Biology (BIOL) 2019, Oxidative Stress Prompts Macrophage Polarization Toward Inflammation in Obesity

Jona Plevin, Biology (BIOL) 2019, Masculinization of the brain via epigenetic modifications of estrogen receptor-α

Jenni Rogan, Biology (BIOL) 2019, Trophic Dynamics, evolutionary maintenance, and predator cognitive patterns in two anti-predator adaptations

Ayumi Sakamoto, Biology (BIOL) 2019, Early Exposure General Anesthesia Induces Cognitive Impairment Through the Dysregulation of BDNF

Jacob Schwartz, Biology (BIOL) 2019, Retinoblastoma Protein Inactivation by the Human Cytomegalovirus Kinase UL97 May Compensate for Increased Nucleoplasmic Lamin During Capsid Nuclear Egress

Tamara Deanne Scott, Biology (BIOL) 2019, Dendritic Cell Susceptibility to HTLV-1 Infection in the Infant Gut Mucosa and Subsequent Development of ATL

Eliza Skoler, Biology (BIOL) 2019, Modulating the Antiviral Immune Response to Respiratory Viral Infection: Short-Chain Fatty Acids and T Regulatory Cells

Mackenzie Smith, Biology (BIOL) 2019, Epigenetic Regulation in Glioblastoma Multiforme by DNA Methylation, Non-Coding RNAs, and Post-Translational Histone Modification Reinforces Cancer Stem Cell Phenotype and Chemoresistance

Emma Stewart, Biology (BIOL) 2019, Mechanisms of microbiota-host crosstalk: how microbial short chain fatty acids influence host lipid metabolism and adiposity

Julian Szieff, Biology (BIOL) 2019, Repression of GABA Inhibition from Parvalbumin Containing Basket Cells in the Prefrontal Cortex as an Epigenetic Model for Cognitive Deficits in Schizophrenia

Maddie Talamantes, Biology (BIOL) 2019, Improving homing-based gene drives in Anopheles to prevent the transmission of Plasmodium falciparum

Zachary Trottier, Biology (BIOL) 2019, Autonomic Nervous System Dysfunction Following Sleep Disturbance: Neurophysiological Mechanisms and Their Implications For Cardiovascular Function

Diana Tyutyunnyk, Biology (BIOL) 2019, The LINC is the Link: A New Hypothesis for Laminopathies

Andrew Wallace-Jackson, Biology (BIOL) 2019, GIT Th17 Cells and HIV: A Balance Between Supporting Viral Success and Combatting Disease Progression

Abby Walling, Biology (BIOL) 2019, DNA Methylation is a Dynamic Process Necessary for Creating and Storing Persistent yet Adaptable Memories

Submissions from 2018

Daniel Evan Atkins, Biology (BIOL) 2018, Blood Runs Thicker than Cerebrospinal Fluid: Interactions Between the Vasculature and B1 Stem Cells in the Neurogenic Subventricular Zone

Gray C. Babbs, Biology (BIOL) 2018, Fractured: Differential Cytokine Signaling in the Type 2 Diabetes Mellitus Bone-Bone Marrow Stem Cell Niche

Francesca Caracci, Biology (BIOL) 2018, The Mediating Role of Silent Synapses in the Incubation of Cocaine Craving

Sandra Elaine Carson, Biology (BIOL) 2018, Hematopoietic Stem Cells Adapt and Survive During Acute Myeloid Leukemia

Avery Cheng, Biology (BIOL) 2018, Functional diversity as a measure for the effects of climate change on ecosystem functioning

Donson Jeryco Allen Cook Gallardo, Biology (BIOL) 2018, The Neurological Basis for Cocaine Addiction

Merrick Thomas Ducharme, Biology (BIOL) 2018, Addiction Related Plastic Mechanisms: A Tale of Shifts in Receptor Permeability

Rebecca Jean Fairchild, Biology (BIOL) 2018, The Role of Neutrophil Extracellular Trap Formation in HIV Infection