Comps, honors papers, and prize-winning works of the Biology Department are featured here. All works have been self-submitted by the student authors. Descriptive information about each work is available to search or browse. Access to the full text of the works is limited to current Carleton affiliates with faculty permission. Learn more about how to submit your work and how to request access to the full text of works.

In addition to this digital archive, physical copies of past Biology comps are available for browsing in the Biology office (Hulings Hall 214).

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Submissions from 2026

Emily Muenzer, Biology (BIOL) 2026, The Invasion, Repression, and Escape of Human Endogenous Retrovirus K and its Implications in Targeted Cancer Therapies

Noah Reid, Biology (BIOL) 2026, Elusive Exosomes: Relationship of Exosomal PD-L1 and KRAS-MEK on Immune Suppression

Submissions from 2025

Jordan Appelbaum, Biology (BIOL) 2025, Beyond Surface Antigens: The Rise of Bispecific TCRm-ADCs in Cancer Immunotherapy

Allison Audette, Biology (BIOL) 2025, Gene Flow and Bt-Crops: Understanding Potential Ecological Consequences

Jens Bartel, Biology (BIOL) 2025, Understanding the Lichen Symbiosis in the Age of Genomics

Sydney Bieber, Biology (BIOL) 2025, Sex Hormones and X Chromosome Inactivation Produce Aberrant T Cell Population Ratios in Systemic Lupus Erythematosus Contributing to a Strong Female Bias

Katrin Birk, Biology (BIOL) 2025, Hybridisation and introgression as conservation tactics in the face of anthropogenic environmental change

Max Borden, Biology (BIOL) 2025, RuBisC-No! Designing Protein-Cage-Based Metabolons to Move Synthetic Carbon Fixation Systems in vivo

Ruairi Brown, Biology (BIOL) 2025, A Surfeit of Stressors: The Effects of Ocean Acidification, Hypoxic Waters, and Increasing Ocean Temperatures on Metacarcinus magister

Kerrigan Candra, Biology (BIOL) 2025, Temperature and ocean acidification impacts on the direct versus indirect developing periwinkle snails

Brian Caplan, Biology (BIOL) 2025, ‭Sex Differences in Ischemic Stroke:‬ ‭ The Role of 17𝛽-Estradiol and Mesenchymal Stem Cells on Modulating Cell Death‬ ‭

Gwen Casey, Biology (BIOL) 2025, Mitigating Methane Emissions From Digestate Composting

Martha Chan, Biology (BIOL) 2025, Asymmetrical Horizontal Gene Transfer Between Parasites and Hosts: Evolutionary Constraints and Functional Implications

Dorothy Chou, Biology (BIOL) 2025, Predicting Crab Survival: The Impacts of Climate Change on the Competitive Dynamic of Hemigrapsus sanguineus and Carcinus maenas

Caroline Crampton, Biology (BIOL) 2025, Peroxisomal Disruptions at the Lipid Droplet Interface: Implications for Insulin Resistance

Caroline Crampton, Biology (BIOL) 2025, Peroxisomal Disruptions at the Lipid Droplet Interface: Implications for Insulin Resistance

Lara Dominguez, Biology (BIOL) 2025, Will a Tick in Time Spread Lyme?: The Future Risk Landscape of Lyme Disease in Urban Greenspaces

Jenna Drummond, Biology (BIOL) 2025, The Role of Alternate Alleles in Instituting Reproductive Isolation in Homoploid Hybrid Speciation

Shira Dubin, Biology (BIOL) 2025, Dynamin-Related Proteins in Apicoplast and Mitochondrial Fission During Plasmodium falciparum Replication

Raquel Germani, Biology (BIOL) 2025, Exploring Multiple Paternity and Female Choice: A Strategy to Enhance Genetic Diversity and Population Viability

Ellen Johnson, Biology (BIOL) 2025, From Sensory Organelle to Evolutionary Catalyst: The Impact of Primary Cilia and Sonic Hedgehog Signaling on Phenotypic Plasticity

Elizabeth Kniser, Biology (BIOL) 2025, S. aureus Biofilm Infections: Regulation of Dispersal Through Agr Quorum-Sensing and Therapeutic Challenges

Padmini Konidena, Biology (BIOL) 2025, Exploring the Role of Ghost Introgression in Species Adaptations

Ezra Kucur, Biology (BIOL) 2025, Climate Challenges in the Intertidal Zone: Pisaster ochraceus’ Response to Sea Star Wasting Disease

Rebecca Lerdau, Biology (BIOL) 2025, Climate Change and Anuran Reproductive Response

Caroline Loescher, Biology (BIOL) 2025, The Role of Climate Change in Shaping Range Shifts and Disease Transmission Dynamics Between Plants and Insects

Josephine MacDonald, Biology (BIOL) 2025, Landscapes of Peril: How Fear of Predators and Parasites Shapes Disease Risk

Kyle Machalec, Biology (BIOL) 2025, Neurodegeneration and Lipid Droplets: From Metabolic Buffer to Cellular Burden

Elizabeth Madigan, Biology (BIOL) 2025, The Plastic Predicament: Bisphenol A’s Contribution to Sex Differences Observed in Autism Spectrum Disorder

Abby Marks, Biology (BIOL) 2025, Copper Resistance and Its Role in Antibiotic Resistance Spillover from Manure

Ben Mazor, Biology (BIOL) 2025, You Are What Eats You: Understanding the Gut Microbiome’s Relationship with Alzheimer’s Disease

Sophie McManus, Biology (BIOL) 2025, Shadowless: Mechanisms of persistence in the symbiosis between Vibrio fischeri and Euprymna scolopes

Caitlin McWilliams, Biology (BIOL) 2025, Managing Introgression Before Genetic Swamping: Evolutionary Risk and Opportunity in Invasive-Native Hybridization

Han Jing Munson, Biology (BIOL) 2025, Zooming in on the telescoping effect: Mechanisms of female opioid use disorder and the role of estradiol

Navya Murahari, Biology (BIOL) 2025, RBM39 Degradation Catalyzed Aberrant Splicing Confers Cellular “Sight” for Human Cancer Immune Response

Mariam Nechiporuk, Biology (BIOL) 2025, Power and Precision: Bispecific TCR mimic antibodies simultaneously hunt down tumor specific antigens and engage potent T cell mediated killing

Sara Negasi, Biology (BIOL) 2025, Targeting the cGAS-STING pathway to Improve Outcomes in Solid Tumors

Emma Neham, Biology (BIOL) 2025, Examining The Role of Seipin and The Lipid Droplet Assembly Factor In Lipid Droplet Biogenesis

Jonathan Nguyen, Biology (BIOL) 2025, Crabby Waters: Seasonal Dynamics and Climate Change Impacts on Callinectes Sapidus

Quan Nguyen, Biology (BIOL) 2025, Exploring the different mechanisms by which Candida albicans Enhances Staphylococcus aureus Virulence in Peritonitis and Oral Candidiasis

Zhanghan Ni, Biology (BIOL) 2025, Quorum Sensing Is Associated with Mechanisms That Cause and Regulate Social Cheating in Microbial Cooperation

Tiffan Nyamao, Biology (BIOL) 2025, Targeting XPO1-Mediated Nuclear Export in Multiple Myeloma: Effects on CAR-T Therapy and the Tumor Microenvironment

Jose Ortega, Biology (BIOL) 2025, From Point A to Point Human: The Journey of H5N1 Towards Sustained Human-to-Human Transmission

Joseph Park, Biology (BIOL) 2025, MamT, a conserved protein in magnetotactic bacteria (MTB), is critical for the effective utilization of iron for growth and maturation of magnetic crystals in magnetosomes and directs the localization of Mms6

Allen Perales, Biology (BIOL) 2025, Sculpting the Immune Response: Modifying the CAR NK Cell Construct Against the Tumor Microenvironment

Henry Petrini, Biology (BIOL) 2025, Bridging the Gap: Lysosome-Peroxisome Membrane Contacts in Storage Disorders and Neuropathy

Nithin Poreddy, Biology (BIOL) 2025, Cancer Catalysts: Extracellular Vesicle-Mediated Horizontal Gene Transfer and Genome Integration in Metastasis

Daanyal Raja, Biology (BIOL) 2025, Crude Consequences: A Comparative Analysis of Oil Spill Impacts on Aerial Versus Submerged Species in Saltmarsh Ecosystems

Moira Rankin, Biology (BIOL) 2025, Introgression in anthropogenic landscapes: Weighing adaptive and maladaptive outcomes of unintentional and intentional introgression events

Edith Reyes Contreras, Biology (BIOL) 2025, Rising Temperatures, Vanishing Forests: The Environmental Drivers of Malaria Transmission

Rhusel Rivera, Biology (BIOL) 2025, Investigating the Role of PPAR𝛾 in Peroxisome-Mediated Sebum Production and the Pathophysiology of Acne Vulgaris

Zoe Rose, Biology (BIOL) 2025, Disruption of Peroxisomal Function in Intestinal Epithelial Cells: Implications for Enterocyte Formation

Mehreen Shahid, Biology (BIOL) 2025, OV-BiTE: Using an Oncolytic Virus to Enhance the Efficacy of T-Cell-Attracting Bispecific Monoclonal Antibodies in Treating Cold Solid Tumors

Katya Sjaastad, Biology (BIOL) 2025, How Do the Fungi Speak to the Trees? The Role of HGT and Small RNA Communication in Enabling the Arbuscular Mycorrhizal Symbiosis

Ingrid Smith, Biology (BIOL) 2025, Enhancing CAR-T Cell Therapy for Solid Tumors: Overcoming Tumor Microenvironment Challenges with SynNotch Receptors and PD-1 Blockades

Amanda Ta, Biology (BIOL) 2025, Exploring the Role of Chlamydia trachomatis as a Co-Factor in HPV-Driven Cervical Cancer

Thea Traw, Biology (BIOL) 2025, “Winning” the Crop Battle: Strategic Targeting of Horizontally Transferred Genes in Herbivorous Insects via RNA Interference

Tatjana Truckses Stephens, Biology (BIOL) 2025, Role of Beta Cell Cilia in Insulin Exocytosis

Ella Wiegman, Biology (BIOL) 2025, Turning Up the Heat: Targeting the Unfolded Protein Response in Dendritic Cells to Improve T-Cell Infiltration and Antitumor Function in Ovarian Cancer

Leo Xiao, Biology (BIOL) 2025, A Horizontal Leg Up: Skewed Incidence and Advantage of Horizontal Gene Transfer between Eukaryotic Parasite and Host

Submissions from 2024

Conor Babcock O'Neill, Biology (BIOL) 2024, Human-Accelerated Regions (HARs) & Schizophrenia: Evidence for a Genetic Driver and Recent Negative Selection

Margaret Blaney, Biology (BIOL) 2024, The Autoimmune and Disease-Specific Susceptibility Tradeoffs of Protective Pathogen-Driven Selection

Paloma Bravo, Biology (BIOL) 2024, Intestinal Epithelial Cells Expressing Toll-like-Receptors Communicate with T Regulatory Cells by Shaping the Commensal Microbial Community to Promote Gut Homeostasis

Kate Burton, Biology (BIOL) 2024, A New Immune System Danger Signal: Virally Induced Celiac Disease

Amy Chen, Biology (BIOL) 2024, Targeting proteins in the midgut of mosquitoes to prevent transmission of the malaria parasite

Natalia Crimmel, Biology (BIOL) 2024, Differential Regulation: Brains, Behavior and Disease

Vanessa Czerniecki, Biology (BIOL) 2024, Disordered Flanking Regions of Viral Short Linear Motifs potentially enhance Antibody Recognition

Sophie Draper, Biology (BIOL) 2024, Early Evolution of Homo sapiens: Origins From a Weakly Structured Stem

Anna Greenlee, Biology (BIOL) 2024, Future consequences of woody encroachment in U.S. grasslands

Abby Ignasiak, Biology (BIOL) 2024, Turn Up the Heat: The Importance of Temperature-Mediated Regulation of fHbp in N. meningitidis

Trevor Jones, Biology (BIOL) 2024, The Molecular Pathology and Therapeutic Potential of Autophagy in Alzheimer's Disease

Jelimo Kaitany, Biology (BIOL) 2024, Influence of Symbiodinium Heat Tolerance is Larger than Scleractinia on Coral Holobiont Recovery after Bleaching

Nicholas Lattal, Biology (BIOL) 2024, The evolutionary implications of adaptive introgression of Neanderthal and Denisovan genes in Eurasian

Makena Layton, Biology (BIOL) 2024, The Gut Microbiome, Leaky Gut and Autoimmunity

Sebastian Lee, Biology (BIOL) 2024, The Role of Gut Microbiota in the Pathogenesis of Major Depressive Disorder and Potential Gut-Targeted Antidepressant Therapies

Alice McClain, Biology (BIOL) 2024, Gardening the reef: future-proofing approaches to coral conservation

Ewan Miller, Biology (BIOL) 2024, A Coordinated Effort: The Recruitment of Regulatory T cells Involves Gut Microbes and the Vagus Nerve

Anya Mitton-Fry, Biology (BIOL) 2024, Latitude and avian life history strategies

Nicholas Moore, Biology (BIOL) 2024, Schizophrenia and the Human Noncoding Revolution: a New Evolutionary Framework

Shreya Nair, Biology (BIOL) 2024, A Gut feeling : Understanding the relationship between Amyotrophic Lateral Sclerosis, the Gut Microbiome and Butyrate

Wanying Na, Biology (BIOL) 2024, The Role of VgrG-Associated Effectors in T6SS Structural Assembly, Firing and Interbacterial Competition of Pseudomonas aeruginosa

Brenna Russell, Biology (BIOL) 2024, Butyrate’s Maintenance of Colonic Homeostasis via PPARγ Activation

Emilie Scott, Biology (BIOL) 2024, α-synuclein and neuroinflammation pathology in Parkinson's Disease and Baicalein as an approach to halting disease progression

Ian Scott, Biology (BIOL) 2024, One Fish, Two fish, Hot Fish, Dead Fish: Effects of Temperature and Flow on Pacific Chinook Salmon

Mira Stephens, Biology (BIOL) 2024, Inhibition of Host Protein Synthesis by Legionella pneumophila as a Strategy for Amino Acid Acquisition and Host Cell Cycle Arrest

Micah Jay Strike, Biology (BIOL) 2024, Water flow as a rescue mechanism for corals during marine heatwaves

Blake Tran, Biology (BIOL) 2024, Saving Salmonids: Preparing Southwest Trout for Heat Waves and a Changing Climate

Vasilii Vaganov, Biology (BIOL) 2024, Decoding the Intricacies of Cajal Body Formation: Unveiling the Sequential Cascade of RNA Seeding, Coilin N-Terminal Oligomerization, and Coilin C-Terminal Recruitment

Isabella Vazquez, Biology (BIOL) 2024, The impact of heatwaves on temperature-dependent sex determination mechanisms in Trachemys scripta elegans

Aniketh Vipparla, Biology (BIOL) 2024, Duel of the Fates: Type VI Secretion System versus Biofilm in Acinetobacter baumannii Virulence

Jisoo Yeom, Biology (BIOL) 2024, Deciphering the Role of Phosphorylation in Period2 Using Frequency as a Model

Submissions from 2023

Collin Adams, Biology (BIOL) 2023, The Multifaceted Role of Codon Usage Bias in Regulating Gene Expression

Kelsie Armstrong, Biology (BIOL) 2023, Acclimation and Fluctuating Temperatures Affect Ecological Performance and Development in Frogs

Sophie Baggett, Biology (BIOL) 2023, Alzheimer's Disease: Turning Towards Tau

Aaron Berkowitz, Biology (BIOL) 2023, ApoE-TREM 2 Interaction: An Important Regulator of Alzheimer’s Disease Pathogenesis

Maddie Boulis, Biology (BIOL) 2023, Human Cytomegalovirus RNA2.7 aids Viral Immune Evasion

Ross Burnside, Biology (BIOL) 2023, Common Is Not Always Optimal: The Reasons for Using Rare Codons in Genes

Emma Carlson, Biology (BIOL) 2023, Codon usage bias as a regulatory mechanism of gene expression

Isabella Charlton, Biology (BIOL) 2023, Regulation of Abiotic Stress Response in Arabidopsis Via Alternative Splicing

Eleanor Chen, Biology (BIOL) 2023, Torpor-Associated Thermoregulation and Appetite Regulation in Endothermic Mammals: A Concerted and Tailored Process