Carleton Author

Abrams, Kenneth; Sawtell, Shaun

Department

Psychology

Journal Title

Addictive Behaviors

Publication Date

2008

First Page

1463

Publisher

Elsevier

Last Page

1469

File Name

039_Abrams-Kenneth_BiologicalChallengeProceduresUsedToStudyNicotine.pdf

Keywords

Nicotine dependence, Smoking, Panic disorder, Biological challenges, Comorbidity

Abstract

A wide array of biological challenge procedures – including carbon dioxide inhalation, hyperventilation, and breath holding – have been used to model panic in laboratory settings. Originally used to study developmental processes in panic disorder (PD), these procedures, along with nicotine patch administration and self-administered smoking, have recently been applied to help understand the etiology of co-occurring nicotine dependence and PD. The goals of the present paper are to review studies that have employed biological challenges to study the comorbid condition, identify the advantages and limitations of the various procedures, describe desirable outcome measures for use in biological challenges, and present recommendations for future challenge studies in this field. We argue that biological challenges, though in need of standardization, are useful for studying the development, maintenance, prevention, and treatment of comorbid nicotine dependence and PD.

Rights Management

Carleton College does not own the copyright to this work and the work is available through the Carleton College Library following the original publisher's policies regarding self-archiving. For more information on the copyright status of this work, refer to the current copyright holder.

RoMEO Color

Green

Preprint Archiving

Yes (with link to journal home page)

Postprint Archiving

Yes

Publisher PDF Archiving

No

Contributing Organization

Carleton College

Type

Article

Format

application/pdf

Language

English

Included in

Psychology Commons

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